Berberine 500mg


Regular Price: $29.95

Special Price $23.95

• Supports Healthy Endocrine, Cardiovascular, and Immune Systems

• Promotes Healthy Body Weight

• Beneficial for Overall Intestinal Health

  • Description
  • Supplement Facts
  • FAQs
  • Reviews
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  • Berberine is a natural alkaloid that has been used for thousands of years by healers in both Chinese and Ayurvedic medicines.  Numerous research studies have shown berberine to be a powerful anti-oxidant and anti-inflammatory1 element in addition to an effective antimicrobial agent2 possibly reducing the need for antibiotics.  With an increased understanding of its method of action, and numerous health benefits, Berberine continues to be a beneficial supplement in modern-day medicine.  

    Berberine triggers the AMPK enzyme3, which is the enzyme that controls energy production and utilization, helps to improve blood sugar levels4, reduces cholesterol and fat deposits5, improves blood pressure and boosts metabolism ultimately helping to control weight and reduce disease risk.  

    In addition, ongoing studies are showing potential benefits of berberine supplementation in regards to neurological conditions6.  Berberine limits the genesis of amyloid plaques and neurofibrillary tangles, which are known to contribute to Alzheimer’s Disease, while protecting against oxidative stress and neuroinflammation7.  

    Health Thru Nutrition’s Berberine HCL is manufactured in a cGMP facility in the United States and tested by ultra-high-performance liquid chromatography to ensure accurate potency levels at a minimum of 100% of the label claim – meaning you receive the benefits of all 500mg of berberine in one easy to swallow vegetarian capsule!  HTN uses PhytoSure™ Berberine, which is a certification mark of CAS BioSciences, LLC, all rights reserved; Phytosure™ is a triple verified true product, non-GMO, 100% plant guaranteed, authenticated and certified, and is an assurance of the strictest quality standards.  

    Health Thru Nutrition’s Berberine HCL is specially formulated to help you receive optimal results! 

    1 The anti-inflammatory potential of berberine in vitro and in vivo Kuo, Chi-Li et al. Cancer Letters , Volume 203 , Issue 2 , 127 - 137
    2 Antimicrobial Activity of Berberine Alone and in Combination with Ampicillin or Oxacillin Against Methicillin-Resistant Staphylococcus aureus Hyeon-Hee Yu, Kang-Ju Kim, Jeong-Dan Cha, Hae-Kyoung Kim, Young-Eun Lee, Na-Young Choi, and Yong-Ouk You.Journal of Medicinal Food.Dec 2005.ahead of print
    3 Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States Yun S. Lee, Woo S. Kim, Kang H. Kim, Myung J. Yoon, Hye J. Cho, Yun Shen, Ji-MingYe, Chul H. Lee, Won K. Oh, Chul T. Kim, Cordula Hohnen-Behrens, Alison Gosby, Edward W. Kraegen, David E. James, Jae B. Kim Diabetes Aug 2006, 55 (8) 2256-2264; DOI: 10.2337/db06-0006
    4 Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression Zhang, Hao et al. Metabolism - Clinical and Experimental , Volume 59 , Issue 2 , 285 - 292
    5 Dong, H., et al. “The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials.” Planta Med 79, no. 6 (2013): 437-446.
    6 Sci China Life Sci. 2015 Jun;58(6):564-9. doi: 10.1007/s11427-015-4829-0. Epub 2015 Mar 6. Therapeutic potential of berberine against neurodegenerative diseases. Jiang W1, Li S, Li X.
    7 Neuropsychiatr Dis Treat. 2016; 12: 2509–2520. Published online 2016 Oct 3. doi:  10.2147/NDT.S114846 Role of berberine in Alzheimer’s disease Zhiyou Cai,1,* Chuanling Wang,1,* and Wenming Yang2
  • Other Ingredients: Hypromellose, dicalcium phosphate anhydrous, non-GMO vegetable magnesium stearate, silicon dioxide and L-Leucine.

    Free of: milk, egg, fish, shellfish, tree nuts, wheat or gluten containing grains, peanuts, and soybeans or soy. (Gluten Free, Soy Free, Non-GMO) 

    Directions: Adults: Take one (1) vege-capsule daily with meals as a dietary supplement or as recommended by your healthcare professional. 


    If you are pregnant or nursing a baby, seek the advice of a health professional before using this product. Keep bottle tightly closed. Store in a cool, dry place at controlled room temperature 15°C-30°C (59°F-86°F).Do not refrigerate. 

    Do not exceed the recommended daily dose. Food supplements are not a substitute for a varied diet.

    Exclusively Formulated and Manufactured in a US cGMP Certified Facility

  • Are there any allergens in this product? 

    There are NO allergens in this product.

    Is the capsule made from animal gelatin?

    No, these capsules are pure Non-GMO vegetable and plant materials. And rest assured we do not test on animals either!

    Where is the product made? 

    This product has been manufactured in a certified cGMP U.S. facility in either New York or Maryland. 

    Do You Perform Product and Raw Material Testing? 

    Absolutely YES! Prior to manufacture, we test every single raw material active and inactive, to confirm the identity of each batch of raw material to be used in the finished product. This verified raw material is then lab tested for potency, microbiology, heavy metals, and residual solvents before any use in manufacturing.

    Finally, all finished products are tested to ensure that the potency is at least 100% of label claim, along with a second round of heavy metal and microbiological testing to make sure that the product is safe for human consumption.

    What is magnesium stearate? Why is it added to the supplement? 

    Magnesium stearate is used in the manufacturing of both supplements and medications as a lubricant or “flow agent” to prevent blockages in the machinery. Being used in the manufacturing process, small amounts make their way into the final product. 

    Magnesium stearate is found in nature and in our diet, (meat and chocolate are particularly rich sources). Bottom line, the small amount that you will actually consume from supplements or medications is considered negligible.

    What is silicon dioxide? Why is it added to the supplement? 

    Silicon Dioxide is used in the manufacturing process to prevent the various powdered ingredients destined for the supplement from sticking together and to ensure an even distribution of ingredients in the final product. As with many food additives, consumers often have concerns about finding silicon dioxide on product labels. However, numerous studies have found no health risks associated with silicon dioxide and the actual amount in each supplement is considered negligible.

    What is hypromellose? Why is it added to the supplement? 

    Hypromellose, is a derivative of cellulose, (the main constituent of plant cell walls), used as eye drops for artificial tears and in supplements as an excipient. Hypromellose is a vegetarian alternative to gelatin.

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